Workshop on COVID-19 Public Policies at MIT

The Quest for Open Science: Truth of Covid19 Policy Response

Serious Adverse Events of Special Interest Following mRNA Vaccination in Randomized Trials

June, 2022


Introduction: In 2020, prior to COVID-19 vaccine rollout, the Coalition for Epidemic Preparedness Innovations and Brighton Collaboration created a priority list, endorsed by the World Health Organization, of potential adverse events relevant to COVID-19 vaccines. We leveraged the Brighton Collaboration list to evaluate serious adverse events of special interest observed in phase III randomized trials of mRNA COVID-19 vaccines.