September, 2021
Highlights
• Bulk of COVID-19 per capita deaths occur in elderly with high comorbidities.
• Per capita COVID-19 deaths are negligible in children.
• Clinical trials for these inoculations were very short-term.
• Clinical trials did not address long-term effects most relevant to children.
September, 2021
In brief:
Xu et. al developed a miniature CRISPR system for genome engineering via protein and guide RNA engineering. Whereas the natural Cas12f does not function in mammalian cells, engineered Cas12f mutants, named CasMINI, show comparable activities with Cas12a for efficient gene activation. CasMINI also enables robust gene editing and base editing.
Highlights
September, 2021
Highlights
• Cortical neurons are well approximated by a deep neural network (DNN) with 5–8 layers
• DNN’s depth arises from the interaction between NMDA receptors and dendritic morphology
• Dendritic branches can be conceptualized as a set of spatiotemporal pattern detectors
• We provide a unified method to assess the computational complexity of any neuron type
Summary
August, 2021
Abstract
Background: Reports of waning vaccine-induced immunity against COVID-19 have begun to surface. With that, the comparable long-term protection conferred by previous infection with SARS-CoV-2 remains unclear.
May, 2021
Abstract
COVID-19 is an ongoing global outbreak of coronavirus disease 2019, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The World Health Organization (WHO) declared the outbreak a Public Health Emergency of International Concern on January 30, 2020; and a pandemic on March 11, 2020.
August, 2021
Abstract
Background:
Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials.
Areas of uncertainty:
We assessed the efficacy of ivermectin treatment in reducing mortality, in secondary outcomes, and in chemoprophylaxis, among people with, or at high risk of, COVID-19 infection.
Data sources:
August, 2021
Highlights
Abstract